Parexel, TriNetX partner to advance RWD in clinical trials


Global contract analysis group (CRO) Parexel and healthcare analysis specialist TriNetX are collaborating on a undertaking looking for to enhance entry to and use of real-world information in clinical analysis. Together with healthcare information analysts at Datavant, the companions purpose to join to healthcare information, in order to help growth of richer insights in the hopes of accelerating the execution of analysis.

According to the businesses, the built-in providing will leverage Datavant’s privacy-protecting linking know-how, in order to join Parexel’s research operations information with de-identified information from TriNetX’s world healthcare group community. The intent is to successfully streamlining entry to RWD, to assist improve clinical trials and produce new therapies to market quicker.

Michelle Hoiseth, chief information officer for Parexel, mentioned the worldwide pandemic has induced curiosity in RWD and different superior applied sciences to unfold in the trade.

Our industry has been moving toward more widespread use of real-world data to support clinical development, accelerated by the COVID-19 crisis and informed by new regulatory guidance,​” she mentioned. “Access to richer real-world data on-demand has become even more critical​.”

“Together with TriNetX and Datavant, Parexel has taken an important step forward in its strategy to connect data in a manner that complies with privacy regulations and our data policies at the patient level, bringing the right patient to the right trial at the right time to significantly enhance and accelerate clinical development,” Hoiseth added.

TriNetX’s built-for-purpose person interface and analytics capabilities reportedly make it potential to streamline workflows in research modelling and resolution making. The intent behind the mix of  capabilities is to ship extra significant entry to site-level information, enabling Parexel and its clients to decide what number of sufferers meet the factors and (through use of real-time situation modeling) gauge how completely different variables would possibly affect affected person eligibility.

At that time, information reportedly could be shared with the clinical website, which researchers can use to establish sufferers and start enrollment, saving time in the execution of real-world information research. Peyton Howell, Parexel’s government vice chairman and chief business/technique officer, mentioned, “We are already collaborating together on several COVID-19-related research efforts with the potential to change how we use real-world data in clinical research​.”

Gadi Lachman, TriNetX, added, “We have seen first-hand during the COVID-19 pandemic the potential of real-world data to transform the clinical trial process and bring new therapies to patients faster. This collaboration will enhance the use of real-world evidence at the site level where we see the closest interaction with patients​.”

Datavant’s privacy-protecting linking know-how reportedly permits sponsors and websites to rapidly, safely and simply change de-identified information. The info permits them to make choices about website and feasibility, in order that they will obtain extra speedy startup and higher execution.

Integrating real-world data into the clinical development process has the potential to increase the amount of information gained from each trial, and thus dramatically accelerate the drug development process​,” mentioned Travis May, CEO of Datavant. “We are proud to be working with both Parexel and TriNetX to enhance such real-world data studies by allowing clinical trial data to be linked to real-world data while ensuring regulatory compliance and protecting patient privacy.​”